STRATEGIC PLANNING CASE STUDIES

CASE STUDY: Portfolio strategy

CASE STUDY: 

For this small venture capital-backed biotech, we identified and prioritized a list of targets that would diversify their portfolio across various disease areas.

CLIENT SITUATION:

  • Client is a small venture capital-backed biotech
  • Client needed to identify what near-term research programs they should pursue that leveraged their proprietary technology
  • Goal was to conduct a structured, data-driven prioritization process that built a portfolio of development candidates that would be attractive to potential partners

TRINITY'S ROLE:

  • Trinity conducted a multi-stage project that resulted in 7 lead research programs for the biotech to consider
  1. Identified an initial list of biological targets (eg, enzymes, receptors) amenable to the client’s technology
  2. Matched targets to clinically relevant indications; indications were then ranked by commercial potential and R&D “fit”
  3. Top indications were then “flipped” back to their target, and product concepts were generated for these prioritized targets
  4. Product concepts were validated by KOL interviews and additional research
  5. Prioritized targets and strategic options were presented to the client

ILLUSTRATIVE EXAMPLES:

Prioritization of indications

Indications grouped according to commercial opportunity and R&D feasibility

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Strategic recommendations

Therapeutic area influenced the strategic opportunity for each target

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PROJECT OUTCOMES:

The prioritized targets afforded a diversified portfolio across disease areas, in addition to a range of partnering and commercialization opportunities

  • Biotech’s BoD decided to concentrate initial R&D efforts on four of the targets that Trinity identified